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VEOZAH IS A HORMONE-FREE TREATMENT OPTION

for moderate to severe hot flashes and night sweats due to menopause

WHAT’s VEOZAH?

VEOZAH (fezolinetant) is an FDA-approved prescription treatment for moderate to severe VMS (Vasomotor Symptoms)—also known as hot flashes and night sweats—due to menopause.

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HOW DOES
VEOZAH WORK?

Unlike anything else, VEOZAH directly blocks a source of hot flashes. It works in your hypothalamus—the area of your brain that controls body temperature.

What is VEOZAH™ (fezolinetant) | VMS due to Menopause

How VEOZAH Works

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Transcript +

How VEOZAH Works

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MOA Video

03:07 min

Science has revealed that VMS—also known as Vasomotor Symptoms, the medical name for hot flashes and night sweats due to menopause—isn’t caused by declining estrogen alone.

In fact, we know that a brain chemical called Neurokinin B, or NKB for short, is a trigger of VMS. NKB is found in the temperature control center of your brain, the hypothalamus.

When NKB binds to the receptor in the hypothalamus during menopause it triggers hot flashes and night sweats.

VEOZAH is the first prescription treatment of its kind for moderate to severe Vasomotor Symptoms (VMS) due to menopause.

VEOZAH is designed to directly block NKB from binding to the receptor. This reduces hot flashes and night sweats due to menopause.

What is VEOZAH™ (fezolinetant)?

VEOZAH is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. VEOZAH is not a hormone. Vasomotor symptoms are the feelings of warmth in the face, neck, and chest, or sudden intense feelings of heat and sweating (“hot flashes” or “hot flushes”).

IMPORTANT SAFETY INFORMATION

Do not use VEOZAH if you:

  • have cirrhosis.
  • have severe kidney problems or kidney failure.
  • are taking certain medicines called CYP1A2 inhibitors. Ask your healthcare provider if you are not sure.

Before you use VEOZAH, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver disease or problems.
  • have kidney problems.
  • have any medical conditions that may become worse while you are using VEOZAH.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. VEOZAH may affect the way other medicines work, and other medicines may affect how VEOZAH works.

What are the possible side effects of VEOZAH?

VEOZAH can cause serious side effects, including:

  • increased liver blood test values. Your healthcare provider will do a blood test to check your liver before you start taking VEOZAH. Your healthcare provider will also do this blood test at month 3, month 6, and month 9 after you start taking VEOZAH.

Call your healthcare provider right away if you have the following signs and symptoms of liver problems:

  • nausea
  • vomiting
  • yellowing of the eyes or skin (jaundice)
  • pain in the right upper stomach (abdomen)

The most common side effects of VEOZAH include:

  • stomach (abdominal) pain
  • diarrhea
  • difficulty sleeping (insomnia)
  • back pain
  • hot flashes or hot flushes

These are not all the possible side effects of VEOZAH. Tell your healthcare provider if you have any side effect that bothers you or does not go away.

Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, talk to your healthcare provider and see Patient Product Information for VEOZAH (fezolinetant).

BACK

VEOZAH is the first and only treatment designed to specifically block neurokinin B (NKB). NKB is a chemical that binds to a receptor in your brain, triggering hot flashes and night sweats due to menopause.

STARTING THE
CONVERSATION

with your doctor

VMS is a real medical condition worth talking about, so let's get talking!

 

Take this quick quiz to help you get the treatment conversation started with your doctor.

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  • Answer 8 questions about the impact of hot flashes.
  • Save or print your personalized Doctor Discussion Guide.
  • Use your personalized Doctor Discussion Guide to help start a conversation about VMS treatment options with your healthcare provider.

WHAT ARE THEPOSSIBLE
SIDE EFFECTS

of VEOZAH?

  • Do not use VEOZAH if you have cirrhosis, severe kidney problems, or kidney failure.
  • Do not use VEOZAH if you are taking certain medicines called CYP1A2 inhibitors. Ask your healthcare provider if you are not sure.
  • VEOZAH can cause serious side effects, including increases in liver blood test values. Your healthcare provider will do a blood test to check your liver before you start taking VEOZAH. Your healthcare provider will also do this blood test at month 3, month 6, and month 9 after you start taking VEOZAH. Call your healthcare provider right away if you have the following signs and symptoms of liver problems: nausea, vomiting, yellowing of the eyes or skin (jaundice), pain in the upper right stomach (abdomen).
  • The most common side effects of VEOZAH are stomach (abdominal) pain, diarrhea, difficulty sleeping, back pain, and hot flashes or hot flushes.