Frequently askedquestions

ABOUT VEOZAH

VEOZAH is a prescription medicine used to reduce moderate to severe Vasomotor Symptoms (VMS) due to menopause. VEOZAH is not a hormone.

VEOZAH is the first and only prescription treatment to directly block a source of hot flashes.

VMS—also known as hot flashes and night sweats—are the feelings of warmth in the face, neck, and chest, or sudden intense feelings of heat and sweating, commonly experienced during menopause.

Science has revealed that VMS—also known as Vasomotor Symptoms, the medical name for hot flashes and night sweats—due to menopause isn't caused by declining estrogen alone.

In fact, we know that a brain chemical called Neurokinin B, or NKB for short, is a trigger of VMS. NKB is found in the temperature control center of your brain, the hypothalamus.

When NKB binds to the receptor in the hypothalamus during menopause it triggers hot flashes and night sweats.

VEOZAH is the first prescription treatment of its kind for moderate to severe Vasomotor Symptoms (VMS) due to menopause.

VEOZAH is designed to directly block NKB from binding to the receptor. This reduces hot flashes and night sweats due to menopause.

TAKING VEOZAH

Take VEOZAH exactly as your healthcare provider tells you to take it.

VEOZAH is taken as one tablet, once a day, as prescribed by your healthcare provider. Take VEOZAH with or without food at about the same time each day. Swallow the VEOZAH tablet whole with liquid. Do not cut, crush, or chew the tablet.

If you miss a dose of VEOZAH, take the missed dose as soon as possible that same day. But if your next scheduled dose is less than 12 hours away, just wait until the next day. Return to your normal schedule the following day.

VEOZAH was proven to reduce the number and severity of hot flashes and night sweats*, in as early as one week.

*Based on clinical studies measuring efficacy at 4 and 12 weeks.

Individual results may vary. Talk with your healthcare provider about what this may
mean for you.

Do not take VEOZAH with certain medicines called CYP1A2 inhibitors. Ask your healthcare provider if you are not sure. Make sure to tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. VEOZAH may affect the way other medicines work, and other medicines may affect how VEOZAH works. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine.

Do not use VEOZAH if you have cirrhosis, severe kidney problems, or kidney failure.

Do not take VEOZAH if you are taking certain medicines called CYP1A2 inhibitors. Ask your healthcare provider if you are not sure.

Before taking VEOZAH, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver disease or problems.
  • have kidney problems.
  • have any medical conditions that may become worse while you are using VEOZAH.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

VEOZAH may affect the way other medicines work, and other medicines may affect how VEOZAH works. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine.

GETTING VEOZAH

VEOZAH is a prescription medication for moderate to severe VMS (Vasomotor Symptoms) due to menopause. You’ll need to visit your healthcare provider to see if it’s the right option for you.

Looking for more VEOZAH resources? Check out our Savings and Support page.

SIDE EFFECTS

VEOZAH can cause serious side effects, including:

  • increased liver blood test values. Your healthcare provider will do a blood test to check your liver before you start taking VEOZAH. Your healthcare provider will also do this blood test at month 3, month 6, and month 9 after you start taking VEOZAH.

Call your healthcare provider right away if you have the following signs and symptoms of liver problems:

  • nausea
  • vomiting
  • yellowing of the eyes or skin (jaundice)
  • pain in the right upper stomach (abdomen)

The most common side effects of VEOZAH include:

  • stomach (abdominal) pain
  • diarrhea
  • difficulty sleeping (insomnia)
  • back pain
  • hot flashes or hot flushes

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all the possible side effects of VEOZAH. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088.

FAQs | VEOZAH™ (fezolinetant) for VMS due to Menopause

How VEOZAH Works

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Transcript +

How VEOZAH Works

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MOA Video

03:07 min

Science has revealed that VMS—also known as Vasomotor Symptoms, the medical name for hot flashes and night sweats due to menopause—isn’t caused by declining estrogen alone.

In fact, we know that a brain chemical called Neurokinin B, or NKB for short, is a trigger of VMS. NKB is found in the temperature control center of your brain, the hypothalamus.

When NKB binds to the receptor in the hypothalamus during menopause it triggers hot flashes and night sweats.

VEOZAH is the first prescription treatment of its kind for moderate to severe Vasomotor Symptoms (VMS) due to menopause.

VEOZAH is designed to directly block NKB from binding to the receptor. This reduces hot flashes and night sweats due to menopause.

What is VEOZAH™ (fezolinetant)?

VEOZAH is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. VEOZAH is not a hormone. Vasomotor symptoms are the feelings of warmth in the face, neck, and chest, or sudden intense feelings of heat and sweating (“hot flashes” or “hot flushes”).

IMPORTANT SAFETY INFORMATION

Do not use VEOZAH if you:

  • have cirrhosis.
  • have severe kidney problems or kidney failure.
  • are taking certain medicines called CYP1A2 inhibitors. Ask your healthcare provider if you are not sure.

Before you use VEOZAH, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver disease or problems.
  • have kidney problems.
  • have any medical conditions that may become worse while you are using VEOZAH.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. VEOZAH may affect the way other medicines work, and other medicines may affect how VEOZAH works.

What are the possible side effects of VEOZAH?

VEOZAH can cause serious side effects, including:

  • increased liver blood test values. Your healthcare provider will do a blood test to check your liver before you start taking VEOZAH. Your healthcare provider will also do this blood test at month 3, month 6, and month 9 after you start taking VEOZAH.

Call your healthcare provider right away if you have the following signs and symptoms of liver problems:

  • nausea
  • vomiting
  • yellowing of the eyes or skin (jaundice)
  • pain in the right upper stomach (abdomen)

The most common side effects of VEOZAH include:

  • stomach (abdominal) pain
  • diarrhea
  • difficulty sleeping (insomnia)
  • back pain
  • hot flashes or hot flushes

These are not all the possible side effects of VEOZAH. Tell your healthcare provider if you have any side effect that bothers you or does not go away.

Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, talk to your healthcare provider and see Patient Product Information for VEOZAH (fezolinetant).

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